this post was submitted on 28 Jun 2025
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Migraine

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Do you take migraine medications like gepants, triptans, or monoclonal antibodies? How well do they work for you? Here's why migraine meds don't work for everyone, and what progress science still needs to make.

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[โ€“] [email protected] 3 points 5 days ago (1 children)

I've been on a CGRP inhibitor (erenumab) since September that took me from neverending to chronic, but it only lasts for three weeks at a time. The fourth week before the next dose is a total wash.

Triptans only work during the first three weeks, so I use diphenhydramine and caffeine with a strong ginger tea chaser to cope ๐Ÿ˜ตโ€

[โ€“] [email protected] 2 points 5 days ago

I've recent started CGRP inhibitors and I'm finding a fairly similar thing. I'm very happy to be (almost) migraine free for 3 weeks, but this last week has been so frustrating.

Not only does my head hurt, but my productivity has dropped to almost zero. I hate it.

I wish I could get the injections every 3 weeks, but that doesn't seem to be an option.