this post was submitted on 18 Aug 2023
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I was talking to my hairdresser last week and she loves injections. Guess she forgets enough that pills everyday are too much for her. I'm taking mine in the morning, evening and then progesterone right before bed. So, three times a day I have to take pills. Guess I'm curious what your thoughts about the differences are and if it's just about convenience, as the injections are only once a week, or are there any other benefits one way or the other.

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[–] Entertainmeonly@lemmy.blahaj.zone 5 points 2 years ago (7 children)

Monotherapy. I've heard that word used before, are you saying you don't take any blockers? Or progesterone? How's that work?

[–] NoStressyJessie@lemmy.blahaj.zone 5 points 2 years ago (6 children)

Yeah, I’m just taking a large enough dose that testosterone is nuked by itself. I can add progesterone later, but I’m early in my medical transition, and have heard it’s better to wait a bit.

[–] Entertainmeonly@lemmy.blahaj.zone 3 points 2 years ago (5 children)

I heard if you take too much estrogen your body reverts it back into testosterone and you go backwards. Arg all this is so frustrating sometimes. Sorry. I'm glad to hear this, now I want to know more cause I really dislike spiro. i asked my plume provider about injections but they only gave me onfo on how to inject and how needles work. Not really what I was looking for from them.

Testosterone can convert to estradiol via aromatase, however there's no metabolic pathway in the other direction.

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