this post was submitted on 14 Mar 2025
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You are welcome. I liked the book and it has relatively recent info. Combining it with Obesity Pillars articles, you can get a very good understanding of modern views on pathophysiology of obesity.
I took a brief look over the handbook, every chapter, and especially the chapters on nutrition and metabolism
I think there are some major gaps that a more updated version of the handbook should cover, such as the previously mentioned carbohydate-insulin model of obesity https://hackertalks.com/post/7617450
If you have time I would highly recommend the ketogenic handbook: the science of therapeutic carbohydrate restriction - https://shop.elsevier.com/books/ketogenic/noakes/978-0-12-821617-0 - it is also available online at the usual places.
While the text isn't focused on obesity it makes a compelling through line between metabolic syndrome, hyperinsulinemia, and the conditions the obesity handbook has associated with obesity.
I did enjoy the opening quote about obesity: To treat obesity, Hippocrates, the “father of medicine,” suggested the following:
In this quote we have :