Danger Dust

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A community for those occupationally exposed to dusts, toxins, pollutants, hazardous materials or noxious environments

Dangerous Dusts , Fibres, Toxins, Pollutants, Occupational Hazards, Stonemasonry, Construction News and Environmental Issues

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Impact of Glucocorticoids on Immune Checkpoint Inhibitor Efficacy and Circulating Biomarkers in Non–Small Cell Lung Cancer Patients (aacrjournals.org)

submitted 6 days ago by [email protected] to c/[email protected]

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Significance:

The impact of corticosteroids, widely prescribed for palliation of cancer-related symptoms, on ICI therapy remains unclear. This study shows that baseline steroid use is a negative independent prognostic factor in patients with NSCLC undergoing ICI therapy and provides insights into the decreased T-cell effector differentiation and utility of predictive blood-based markers by steroids.

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