this post was submitted on 10 Nov 2024
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No Stupid Questions

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There is no such thing as a Stupid Question!

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Pure conjectural or anecdotal but it is my intuition that there is something to it

EDIT: My running theory is related to hormesis or tolerance where the body produces an opposite effect to the ligand to maintain homeostasis and there is not a sufficient dose of the exogenous drug taken to override the body's compensatory reaction

So even tho caffeine is a stimulant (adenosine antagonist) it actually causes the body to produce the opposite reaction, causing the reverse effect of making you sleepy

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[โ€“] [email protected] 5 points 2 months ago

Yup. I used to be able to chug a monster and go to bed. Then I got medicated and I can't do that anymore lol.