this post was submitted on 22 May 2025
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ADHD

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This could be a good new option for those with ADHD who are currently on meds for it.

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[–] [email protected] 84 points 1 month ago* (last edited 1 month ago) (13 children)

This is really interesting. As I was reading the article I was wondering how they were going to wring money out of it, as amlodipine is off patent. Then I got to this part:

“While amlodipine shows promise in preclinical models, it is not currently suitable for use in ADHD in its marketed form,” Karlsson noted. “Further optimization through chemical modification is necessary to enhance CNS selectivity and ensure a favorable therapeutic index in the context of ADHD.”

Classic big pharma. Slightly tweak an existing drug in an insignificant way so that you can get a new patent on it and charge exorbitant prices.

[–] [email protected] 10 points 1 month ago (5 children)

Is it going to still work on blood pressure? I don't like the idea of taking meds because I want to resolve things with diet and exercise when possible, and I'm afraid of side effects. But if I eventually have to start taking a blood pressure medication and the side effect is it makes my ADHD better, I could get on board with that.

[–] [email protected] 17 points 1 month ago* (last edited 1 month ago) (1 children)

They're reformulate it and call it something new. They'll still sell amlodipine for blood pressure.

[–] [email protected] 4 points 1 month ago

Yes, but this poses me with a self identity dilemma. Am I the type of person who takes a blood pressure medication that happens to treat their adhd, or am I more the sort who takes adhd meds which happen to treat their high blood pressure?

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