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Wireguard doesn't necessarily need to have those limitations, but it will depend in part how your VPN profile is set up.
If you configured your wireguard profile to always route all traffic over the VPN then yeah, you won't be able to access local networks. And maybe that's what you want, in which case fine :)
But you can also set the profile to only route traffic that is destined for an address on the target network (I.e your home network) and the rest will route as normal.
This second type of routing only works properly however when there are no address conflicts between the network you are on (i.e. someone else's WiFi) and your home network.
For this reason if you want to do this it's best to avoid on your own home network the common ranges almost everyone uses as default, i.e. 192.168.0.* and 10.0.0.*
I reconfigured my home network to 192.168.22.* for that reason. Now I never hit conflicts and VPN can stay on all the time but only traversed when needed :)
I typically use split routing BUT also have dns set to my pihole, both so dns works for my internal services and for tracker blocking. That causes a big issue. Also I wish WireGuard would just handle failures better. Even when it can’t connect, it seems to break networking (at least on iOS)