For survivor, I almost exclusively play with at least 1 friend, so I'm running a very team-oriented build. I've got Botany Knowledge for faster healing, Sprint Burst for running away, Prove Thyself for crazy generator speed, and Kindred for the team coordination value.
For killer, I play Wraith, Ghost face, and Singularity. Wraith and Singularity have my "good stuff" build: No One Escapes Death, Jolt, and Fear Monger, with Wraith taking Bloodhound as a 4th for better chasing and Sing taking Thrilling Tremors for map info. Ghost face skips Noed (since he has built in exposed), and takes monger, jolt, tremors, and I'm All Ears.
I'm fairly new to the game, so I don't have a ton of perks yet, but I'm pretty happy with my builds so far, they feel really solid and useful even if they're not super synergy or exciting.